Post by Admin on Jul 13, 2015 20:51:16 GMT -5
Lyme Induced Immune Suppression May Bring Lyme Tests into Question
www.cortjohnson.org/blog/2015/07/13/lyme-induced-immune-suppression-brings-lyme-tests-into-question/
There has been a growing consensus that whatever chronic Lyme disease is it’s not due to the bacteria. This concensus has been based on studies indicating that short term antibiotic treatment following an infection causes a dramatic reduction in antibody bodies. That drop in antibody levels is believed to reflect the immune system turning itself off because the bacteria, Borrelia burgdorferi, is gone. This study overturned that idea completely. Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection. Rebecca A. Elsner1,2¤a, Christine J. Hastey1,2¤b, Kimberly J. Olsen1, Nicole Baumgarth1,2,3* PLOS Pathogens | DOI:10.1371/journal.ppat.1004976 July 2, 2015 The Lyme bacteria does more damage than we knew. Borrelia has developed several tricks to evade the immune system. It can inhibit complement activity and disguise itself by varying the proteins found on its surface. How quickly the infection spreads may be a key factor in how easy it is suppress. Infections that stay localized are more easily dealt with. Wider spreading infection are more difficult to contain. Studies suggest that adaptive or long term immunity is hard to come by.
There has been a growing consensus that whatever chronic Lyme disease is it’s not due to the bacteria. This concensus has been based on studies indicating that short term antibiotic treatment following an infection causes a dramatic reduction in antibody bodies. That drop in antibody levels is believed to reflect the immune system turning itself off because the bacteria, Borrelia burgdorferi, is gone. This study overturned that idea completely. Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection. Rebecca A. Elsner1,2¤a, Christine J. Hastey1,2¤b, Kimberly J. Olsen1, Nicole Baumgarth1,2,3* PLOS Pathogens | DOI:10.1371/journal.ppat.1004976 July 2, 2015 The Lyme bacteria does more damage than we knew. Borrelia has developed several tricks to evade the immune system. It can inhibit complement activity and disguise itself by varying the proteins found on its surface. How quickly the infection spreads may be a key factor in how easy it is suppress. Infections that stay localized are more easily dealt with. Wider spreading infection are more difficult to contain. Studies suggest that adaptive or long term immunity is hard to come by.
Read more: Lyme Induced Immune Suppression May Bring Lyme Tests into Question www.cortjohnson.org/blog/2015/07/13/lyme-induced-immune-suppression-brings-lyme-tests-into-question/
Do note this study was done on mice and no human study yet and they may get to it before another 100,000 of us drop like flies. If not thank you for your service. If you note a bit of sarcasm in my wording; really it is nothing compared to how I really feel at this point.
nite all
www.cortjohnson.org/blog/2015/07/13/lyme-induced-immune-suppression-brings-lyme-tests-into-question/
There has been a growing consensus that whatever chronic Lyme disease is it’s not due to the bacteria. This concensus has been based on studies indicating that short term antibiotic treatment following an infection causes a dramatic reduction in antibody bodies. That drop in antibody levels is believed to reflect the immune system turning itself off because the bacteria, Borrelia burgdorferi, is gone. This study overturned that idea completely. Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection. Rebecca A. Elsner1,2¤a, Christine J. Hastey1,2¤b, Kimberly J. Olsen1, Nicole Baumgarth1,2,3* PLOS Pathogens | DOI:10.1371/journal.ppat.1004976 July 2, 2015 The Lyme bacteria does more damage than we knew. Borrelia has developed several tricks to evade the immune system. It can inhibit complement activity and disguise itself by varying the proteins found on its surface. How quickly the infection spreads may be a key factor in how easy it is suppress. Infections that stay localized are more easily dealt with. Wider spreading infection are more difficult to contain. Studies suggest that adaptive or long term immunity is hard to come by.
There has been a growing consensus that whatever chronic Lyme disease is it’s not due to the bacteria. This concensus has been based on studies indicating that short term antibiotic treatment following an infection causes a dramatic reduction in antibody bodies. That drop in antibody levels is believed to reflect the immune system turning itself off because the bacteria, Borrelia burgdorferi, is gone. This study overturned that idea completely. Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection. Rebecca A. Elsner1,2¤a, Christine J. Hastey1,2¤b, Kimberly J. Olsen1, Nicole Baumgarth1,2,3* PLOS Pathogens | DOI:10.1371/journal.ppat.1004976 July 2, 2015 The Lyme bacteria does more damage than we knew. Borrelia has developed several tricks to evade the immune system. It can inhibit complement activity and disguise itself by varying the proteins found on its surface. How quickly the infection spreads may be a key factor in how easy it is suppress. Infections that stay localized are more easily dealt with. Wider spreading infection are more difficult to contain. Studies suggest that adaptive or long term immunity is hard to come by.
Read more: Lyme Induced Immune Suppression May Bring Lyme Tests into Question www.cortjohnson.org/blog/2015/07/13/lyme-induced-immune-suppression-brings-lyme-tests-into-question/
Do note this study was done on mice and no human study yet and they may get to it before another 100,000 of us drop like flies. If not thank you for your service. If you note a bit of sarcasm in my wording; really it is nothing compared to how I really feel at this point.
nite all