Post by alankey on Nov 17, 2008 16:12:12 GMT -5
heres an interesting use for the nanomagnetite that has been detected in morgellons sufferers
www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TWB-4M4CN4F-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=ad4867d731861922f7887026603c6cca
when magnetic nanoparticles such as nanomagnetite are coated with lactobionic acid,it allows the nanomagnetite to enter hepatocytes.
hepatocytes perfom many essential roles,from the transformation of carbohydrates to the synthesis of vital enzymes and protiens
en.wikipedia.org/wiki/Hepatocyte
"The hepatocyte is a cell in the body that manufactures serum albumin, fibrinogen, and the prothrombin group of clotting factors. It is the main site for the synthesis of lipoproteins, ceruloplasmin, transferrin, complement and glycoproteins. Hepatocytes manufacture their own structural proteins and intracellular enzymes.
Synthesis of proteins is undertaken by the rough endoplasmic reticulum (RER), and both the rough and smooth endoplasmic reticulum (SER) are involved in secretion of the proteins formed. The endoplasmic reticulum (ER) is involved in conjugation of proteins to lipid and carbohydrate moieties synthesized by, or modified within, the hepatocytes."
thus if one can get nanomagnetite to enter hepatocytes one can create some interesting possibilities such as the control of what the hepatocytes manufacture!.
" Nanomagnetic actuation of receptor-mediated signal transduction.
[My paper] Robert J Mannix, Sanjay Kumar, Flávia Cassiola, Martín Montoya-Zavala, Efraim Feinstein, Mara Prentiss, Donald E Ingber
Complex cell behaviours are triggered by chemical ligands that bind to membrane receptors and alter intracellular signal transduction. However, future biosensors, medical devices and other microtechnologies that incorporate living cells as system components will require actuation mechanisms that are much more rapid, robust, non-invasive and easily integrated with solid-state interfaces. Here we describe a magnetic nanotechnology that activates a biochemical signalling mechanism normally switched on by binding of multivalent chemical ligands. Superparamagnetic 30-nm beads, coated with monovalent ligands and bound to transmembrane receptors, magnetize when exposed to magnetic fields, and aggregate owing to bead-bead attraction in the plane of the membrane. Associated clustering of the bound receptors acts as a nanomagnetic cellular switch that directly transduces magnetic inputs into physiological cellular outputs, with rapid system responsiveness and non-invasive dynamic control. This technique may represent a new actuator mechanism for cell-based microtechnologies and man-machine interfaces.
Other papers by authors:"
lib.bioinfo.pl/pmid:18654448
i noticed a link posted by the admin whch explained that our blood is being depleted of copper resulting in many negative outcomes including changes in the rh factor.
one of the protiens that hepatocytes produce is ceruloplasmin
en.wikipedia.org/wiki/Ceruloplasmin
ceruloplasmin main role is carrying of copper in the blood,therefore if one wanted to deplete theblood of copper one has to deplete the production of ceruloplasmin by controling the enzymes and protiens that the magnetite laced hepatocyte produced,aka getting the hepatocytes to not produce ceruloplasmin!
also another molecule that hepatocytes produce is serum ablumin,i had a blood test several months ago and i had an excess of serum albumin and several other compounds such as phosphates,sodium,zinc and pottasium.
it is noted that when lactobionic acid is in excess in the biological system,it produces excesses of the above mentioned compounds!.
and since lactbionic acid is the mechanism which allows nanomagnetite to coalesce with hepatocytes one wonders if a test for labatonic acid is an indicator of ones hepatocytes being infested with nanomagnetite!
one final note is the excess of carbohydrates seen in morgellons sufferers.
"hepatocytes also play a part in carbohydrate synthesis,
The endoplasmic reticulum (ER) is involved in conjugation of proteins to lipid and carbohydrate moieties synthesized by, or modified within, the hepatocytes."
this may or may not be an explanation for that seen abundance.
www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TWB-4M4CN4F-1&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=ad4867d731861922f7887026603c6cca
when magnetic nanoparticles such as nanomagnetite are coated with lactobionic acid,it allows the nanomagnetite to enter hepatocytes.
hepatocytes perfom many essential roles,from the transformation of carbohydrates to the synthesis of vital enzymes and protiens
en.wikipedia.org/wiki/Hepatocyte
"The hepatocyte is a cell in the body that manufactures serum albumin, fibrinogen, and the prothrombin group of clotting factors. It is the main site for the synthesis of lipoproteins, ceruloplasmin, transferrin, complement and glycoproteins. Hepatocytes manufacture their own structural proteins and intracellular enzymes.
Synthesis of proteins is undertaken by the rough endoplasmic reticulum (RER), and both the rough and smooth endoplasmic reticulum (SER) are involved in secretion of the proteins formed. The endoplasmic reticulum (ER) is involved in conjugation of proteins to lipid and carbohydrate moieties synthesized by, or modified within, the hepatocytes."
thus if one can get nanomagnetite to enter hepatocytes one can create some interesting possibilities such as the control of what the hepatocytes manufacture!.
" Nanomagnetic actuation of receptor-mediated signal transduction.
[My paper] Robert J Mannix, Sanjay Kumar, Flávia Cassiola, Martín Montoya-Zavala, Efraim Feinstein, Mara Prentiss, Donald E Ingber
Complex cell behaviours are triggered by chemical ligands that bind to membrane receptors and alter intracellular signal transduction. However, future biosensors, medical devices and other microtechnologies that incorporate living cells as system components will require actuation mechanisms that are much more rapid, robust, non-invasive and easily integrated with solid-state interfaces. Here we describe a magnetic nanotechnology that activates a biochemical signalling mechanism normally switched on by binding of multivalent chemical ligands. Superparamagnetic 30-nm beads, coated with monovalent ligands and bound to transmembrane receptors, magnetize when exposed to magnetic fields, and aggregate owing to bead-bead attraction in the plane of the membrane. Associated clustering of the bound receptors acts as a nanomagnetic cellular switch that directly transduces magnetic inputs into physiological cellular outputs, with rapid system responsiveness and non-invasive dynamic control. This technique may represent a new actuator mechanism for cell-based microtechnologies and man-machine interfaces.
Other papers by authors:"
lib.bioinfo.pl/pmid:18654448
i noticed a link posted by the admin whch explained that our blood is being depleted of copper resulting in many negative outcomes including changes in the rh factor.
one of the protiens that hepatocytes produce is ceruloplasmin
en.wikipedia.org/wiki/Ceruloplasmin
ceruloplasmin main role is carrying of copper in the blood,therefore if one wanted to deplete theblood of copper one has to deplete the production of ceruloplasmin by controling the enzymes and protiens that the magnetite laced hepatocyte produced,aka getting the hepatocytes to not produce ceruloplasmin!
also another molecule that hepatocytes produce is serum ablumin,i had a blood test several months ago and i had an excess of serum albumin and several other compounds such as phosphates,sodium,zinc and pottasium.
it is noted that when lactobionic acid is in excess in the biological system,it produces excesses of the above mentioned compounds!.
and since lactbionic acid is the mechanism which allows nanomagnetite to coalesce with hepatocytes one wonders if a test for labatonic acid is an indicator of ones hepatocytes being infested with nanomagnetite!
one final note is the excess of carbohydrates seen in morgellons sufferers.
"hepatocytes also play a part in carbohydrate synthesis,
The endoplasmic reticulum (ER) is involved in conjugation of proteins to lipid and carbohydrate moieties synthesized by, or modified within, the hepatocytes."
this may or may not be an explanation for that seen abundance.