Post by skytroll on Oct 2, 2007 0:15:32 GMT -5
Evolution is destroying us, chemtrails are making it so.
Evolution, Ecology, Environment
IEEE and more...........It is about changing the species of man.
No aliens, but the kerogens, synthetic they are, tholins are not.
Dark matter, only operates in the shadows.
But, the real, is also out there.
Programmed Evolution:
Bout time they did some d**n VERIFICATION.
This article needs additional references or sources for verification.
Please help improve this article by adding reliable references. Unverifiable material may be challenged and removed.
Programmed evolution is an evolutionary process akin to natural selection. The main difference between natural selection and programmed evolution is that natural selection relies on random environmental events to eliminate genotype attributes that hinder survival of that species. Programmed evolution is a regulated process in which organisms switch on altered levels (usually higher) of mutagenesis. Usually this is in response to sensed, non-mutagenic environmental cues.
Evidence for programmed evolution include:
faster than expected development of bacteria with antibiotic resistance
existence of multiple, low fidelity DNA polymerases in bacteria regulated by SOS response.
the ability to suppress bacterial MDR evolution by small molecule intervention[1].
Programmed evolution is, however, still mildly controversial amongst certain circles of evolutionary biology, since programmed evolution does not confer survival advantage upon the individual.
A further controversial, but related, concept is directed evolution.
Not controversial anymore, THE GIG IS UP!
Directed evolution
From Wikipedia, the free encyclopedia
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Directed evolution is a method used in protein engineering to harness the power of Darwinian selection to evolve proteins or RNA with desirable properties not found in nature.
A typical directed evolution experiment involves three steps:
Diversification: The gene encoding the protein of interest is mutated and/or recombined at random to create a large library of gene variants. Techniques commonly used in this step are error-prone PCR and DNA shuffling.
Selection: The library is tested for the presence of mutants (variants) possessing the desired property using a screen or selection. Screens enable the researcher to identify and isolate high-performing mutants by hand, while selections automatically eliminate all nonfunctional mutants.
Amplification: The variants identified in the selection or screen are replicated manyfold, enabling researchers to sequence their DNA in order to understand what mutations have occurred.
Together, these three steps are termed a "round" of directed evolution. Most experiments will perform more than one round. In these experiments, the "winners" of the previous round are diversified in the next round to create a new library. At the end of the experiment, all evolved protein or RNA mutants are characterized using biochemical methods.
The likelihood of success in a directed evolution experiment is directly related to the total library size, as evaluating more mutants increases the chances of finding one with the desired properties. Performing multiple rounds of evolution is useful not only because a new library of mutants is created in each round, but because each new library uses better mutants as templates. The experiment is analogous to climbing a hill on a landscape where elevation is a function of the desired property. The goal is to reach the summit, which represents the best mutant. Each round of selection samples mutants on all sides of the starting template and selects the mutant with the highest elevation, thereby climbing the hill. A new round samples mutants on all sides of this new template and picks the highest of these, and so on until the summit is reached.
Directed evolution can be performed in living cells (in vivo evolution) or may not involve cells at all (in vitro evolution). In vivo evolution has the advantage of selecting for properties in a cellular environment, which is useful when the evolved protein or RNA is to be used in living organisms, but in vitro evolution is often more versatile in the types of selections that can be performed. Furthermore, in vitro evolution experiments can generate larger libraries because the library DNA need not be inserted into cells, the currently limiting step.
The advantage of the directed evolution approach is that the researcher need not understand the mechanism of the desired activity in order to improve it. An alternative method is site-directed mutagenesis based on X-ray crystallography data.
Most directed evolution projects seek to evolve properties that are useful to humans in an agricultural, medical or industrial context. It is thus possible to use this method to optimize properties that were not selected for in the original organism. This may include catalytic specificity, thermostability and many others.
right into the d**n computer, thermal imaging...........
en.wikipedia.org/wiki/Directed_evolution
Directed evolution:
www.fraunhofer-cmb.org/index.cfm?act=tech_DirectedEvolution
skytroll